L-Theanine for Anxiety and Depression - Does It Work? Evidence?
L-theanine is a supplement that you can take that has evidence behind it that it will help you reach higher levels of serotonin, dopamine and glycine, and a combination of these increases could help relieve anxiety, reduce stress, and maybe even help some depression. L-theanine is something that is primarily found in green and black tea and some mushrooms, but it's also available in a pill or tablet form. In the image to the right, I've got what I've been taking. This is my bottle of L-theanine.
It's not expensive. I don't remember how much I spent on it. I heard from a family member about the effectiveness of this, and that it's indicated for stress and anxiety. I thought, I've got to check this out for myself. So I went online. I bought that bottle. I've been taking it for a few months now. I'll be honest with you, my experience with it hasn't been earth shattering.
I do think at this time in my life, I've got the things that I take for my anxiety. I take L-Methylfolate, which is another supplement I talk about in an article here. I take Prozac, which is an SSRI. I also take magnesium as a lotion. I supplement that and I talk about that in another article here. Between those three things, plus adding this L-theanine, I've been in the best condition of my life. As far as anxiety goes and my overall mental health, I feel great. I have energy. I'm exercising. I'm going to school full time. I'm working. I also have a lot of other stressors in my life, but I'm able to manage, and I'm able to do it and be happy. I'm not miserable doing all these things. I don't really know how much this L-theanine plays a role in how I'm feeling right now, but I know I feel great, and I know it's something that has the evidence behind it, and I'm going to keep taking it.
I want to talk a little bit about what this does. Like I said, it helps increase your serotonin level, increase your dopamine level, and your Glycine level, but it also increases a protein called brain derived neurotrophic factor, which I talk about a lot in an article here, which helps you learn. Brain Derived Neurotrophic Factor (BDNF) helps your brain adapt and make new connections. It helps you learn, but it also plays a role in mental health, which I talk about in that article. It also increases something called nerve growth factor, which, again, is like BDNF, and helps you make new connections in your brain and within your body. Between all these things, there's a lot of good potential behind L-Theanine use.
“Stress-related symptoms (i.e., depression, anxiety-trait, and sleep) scores decreased and cognitive function (i.e., verbal fluency and executive function) scores improved after four weeks of L-theanine administration. The reduction in sleep quality problems (disturbances in sleep latency, sleep disturbance, and use of sleep medication) was greater in the L-theanine administration compared to the placebo administration.”
It helped with sleep, and it helped with anxiety and depression symptoms. There are some other studies that talk about this as well. But my conclusion is, it's cheap, it's easy to get. I ordered that online on Amazon. I feel great. Don't know how much role it's playing, but there may be people out there who are actually really deficient in this stuff. So a supplement might really help you. It's definitely something to look into. With all supplements, you want to tell your doctor that you're taking it. This is to make sure it doesn't interfere with any other medications that you're taking.
Always be safe. Stay within the dosage range on these. I believe this one has a fairly high dosage range; it's suggested that you take 200 milligrams of L-Theanine at bedtime. That's what I take is the 200 milligrams. This might be an option for you.
Other Articles
Atarax vs. Vistaril for Anxiety: What's the Difference?
Introduction
Anxiety disorders are among the most common psychiatric conditions affecting people today. Nearly 20% of adults in the United States have an anxiety disorder, which can significantly interfere with daily activities and quality of life. While anxiety is a normal human response to stressors, anxiety disorders involve excessive, persistent fear and worry that is out of proportion to the actual situation.
Symptoms of anxiety disorders include feelings of panic, fear, and uneasiness; restlessness; fatigue; irritability; muscle tension; sleep disturbances; and concentration difficulties. Anxiety disorders include generalized anxiety disorder, social anxiety disorder, panic disorder, phobias, and more.
When anxiety begins to negatively impact daily functioning and health, it is important to seek treatment. Treatment options for anxiety disorders include psychotherapy, medications, or a combination approach. Medications can help relieve anxiety symptoms and improve functioning while also undergoing counseling. Two commonly prescribed anti-anxiety medications are Vistaril and Atarax.
What are Vistaril and Atarax?
Vistaril (hydroxyzine pamoate) and Atarax (hydroxyzine hydrochloride) are both antihistamine medications that are used to treat anxiety and panic disorders. They belong to a class of medications called antihistamines, which work by blocking the effects of histamine in the body.
Histamine is a chemical that's released by the body during an allergic reaction. It causes symptoms like itching, sneezing, and runny nose. Antihistamines like Vistaril and Atarax help relieve these symptoms by preventing histamine from attaching to receptors in the body.
In addition to allergies, Vistaril and Atarax are both FDA-approved for the treatment of anxiety and tension associated with anxiety disorders. They help reduce anxiety by affecting activity in the central nervous system. These medications can provide relief from excessive worry, irrational fears, and compulsive behaviors.
Both Vistaril and Atarax are also used off-label to treat nausea and vomiting. Although they are not FDA-approved for these uses, they are commonly prescribed by doctors to help relieve nausea related to motion sickness, chemotherapy, or surgery.
So in summary, Vistaril and Atarax are very similar antihistamine medications that are used for treating anxiety, allergies, nausea, and vomiting. The main difference between them is in their formulations, which we'll discuss more below.
How Vistaril and Atarax Work in the Body
Vistaril and Atarax work in similar ways to treat anxiety and allergic reactions. The active ingredient in both medications is hydroxyzine, which acts as an antihistamine. This means it blocks the effects of histamine in the body. Histamine is a chemical that's released during allergic reactions and leads to symptoms like itching, sneezing, and hives.
By blocking histamine receptors, hydroxyzine helps relieve allergy symptoms and reduce anxiety. Research shows it can also increase GABA (gamma-aminobutyric acid) activity in the brain. GABA is a neurotransmitter that has a calming, relaxing effect. Higher GABA activity reduces anxiety, promotes sleep, and helps control fear responses.
So in summary, Vistaril and Atarax work by:
- Blocking histamine receptors to relieve allergy and anxiety symptoms
- Increasing GABA activity in the brain to promote relaxation and reduce anxiety
The antihistamine and GABA-enhancing effects make these medications useful for treating both allergies and anxiety disorders. They have a sedating effect that helps patients feel calmer and more relaxed.
Effectiveness for Anxiety
Both Vistaril and Atarax are useful for treating anxiety symptoms. They work in a similar way by blocking histamine receptors and reducing activity in the central nervous system.
Studies have found both medications can help relieve symptoms like excessive worrying, restlessness, irritability, panic attacks, and trouble sleeping caused by anxiety disorders.
The main difference when it comes to effectiveness is that Vistaril tends to be more sedating. Atarax can cause drowsiness too, but Vistaril has a greater calming and sleep-promoting effect.
Many doctors prescribe Vistaril specifically for anxiety with insomnia or nighttime symptoms, while they may choose Atarax more often for generalized anxiety during the day. The sedating qualities of Vistaril make it better suited for addressing anxiety symptoms that interfere with sleep.
Overall, both medicines are effective options for anxiety. Vistaril may provide an extra level of relief for individuals who have anxiety with sleep difficulties or pronounced nervousness at night. Discuss your specific symptoms with your doctor to determine whether Vistaril or Atarax is likely to work better in your case.
Dosage
Doctors typically prescribe 25 mg to 100 mg of Vistaril or Atarax daily for anxiety, divided into 2 or 3 doses. The dosage may be adjusted based on the patient's response and tolerability.
For anxiety relief, the starting dosage is often 25 mg two or three times daily. The dosage can be increased every 3-4 days by 25 mg per dose if needed, up to a maximum of 100 mg per dose.
Doctors may prescribe a lower dosage for elderly patients or those with kidney problems, such as 10-25 mg once or twice daily. Children ages 6 months and older are given 0.5 mg per kg of body weight per day, divided into 2-3 doses.
Vistaril and Atarax should be taken with food or milk to minimize stomach upset. The dosage times can be spread evenly throughout the day or taken at bedtime to promote relaxation and sleep. Doctors advise avoiding daytime doses that can cause drowsiness and impair mental alertness.
The time it takes to feel the anti-anxiety effects of Vistaril or Atarax varies by individual. Symptom relief may begin within 30-60 minutes and can last up to 8 hours after taking the medication. Patients will work with their doctor to find the ideal dosage timing and schedule.
Side Effects of Vistaril and Atarax
When comparing the side effects of Vistaril and Atarax, the two medications are very similar. The most common side effects for both drugs include:
**Drowsiness** - Both Vistaril and Atarax can cause drowsiness. However, this side effect may be more pronounced with Atarax, especially when first starting the medication. Vistaril tends to cause less daytime sleepiness.
**Dry mouth** - Dry mouth is commonly reported with both Vistaril and Atarax. This can occur from the anticholinergic properties of the medications. Sipping water and chewing sugarless gum may help.
**Constipation** - Constipation is another possible side effect of Vistaril and Atarax due to their anticholinergic effects. Staying hydrated, eating high fiber foods, and maintaining physical activity can help prevent constipation.
In general, the side effect profiles of these two medications are very similar. However, the severity and frequency of certain side effects like drowsiness may be slightly less with Vistaril compared to Atarax. If side effects become bothersome, adjusting the dosage or timing of the medication may help. Discuss any persisting side effects with your doctor.
Warnings and precautions
When considering Vistaril or Atarax, it's important to be aware of the following warnings and precautions:
- Elderly patients may be more sensitive to the effects of antihistamines and may experience impairment in thinking, judgment, and motor coordination. Vistaril and Atarax should be used with caution in the elderly.
- Pregnant women should only use Vistaril or Atarax if clearly needed. These medications can cross the placenta and potentially cause adverse effects in the fetus. Infants born to mothers taking antihistamines may experience withdrawal symptoms.
- Vistaril and Atarax can potentially interact with many medications. This includes antidepressants, anticholinergics, opiate pain relievers, allergy medications, sleep aids, muscle relaxers, seizure medications, and more. Patients should advise their doctor of all medications they are taking to avoid dangerous interactions.
- Alcohol should be avoided when taking Vistaril or Atarax, as it can increase drowsiness and impairment.
- Vistaril and Atarax may impair mental alertness and physical coordination. Patients should use caution when driving or operating machinery until they know how the medication affects them.
- These medications may increase sensitivity to the sun. Patients should limit sun exposure and wear protective clothing and sunscreen when outdoors.
Knowing the potential risks and how to minimize them allows patients to use Vistaril and Atarax safely under medical supervision. Patients should discuss all concerns with their healthcare provider.
Formulations and administration
Vistaril and Atarax come in several formulations that can be taken orally or administered via injection.
Tablets
- Vistaril is available as 25 mg oral tablets. The typical dosage is 50-100 mg per day in divided doses.
- Atarax comes in 10 mg and 25 mg oral tablets. The recommended dosage for anxiety is 25-50 mg per day split into 2-3 doses.
Capsules
- Atarax 25 mg capsules can be taken instead of tablets. The capsules provide the same dosage and effects.
Syrups
- Both Vistaril and Atarax come in syrup formulations that contain 25 mg per 5 mL. The syrup may be easier to swallow for some patients.
Injections
- Vistaril and Atarax can be given by intramuscular injection when needed for rapid relief of severe anxiety or agitation.
- The injections are only administered under medical supervision. The typical dose is 25-50 mg.
- Injections provide faster onset of effects compared to oral tablets or capsules.
The different formulations offer flexibility in administration. Patients can work with their doctor to determine the best dosage form based on their preferences and needs.
Cost and Availability
Both Vistaril and Atarax are available as inexpensive generic medications, making them affordable treatment options for anxiety.
The generic version of Vistaril (hydroxyzine pamoate) usually costs between $10-$15 for a month's supply without insurance. With insurance coverage, it may only cost a few dollars per month.
Atarax is the brand name for hydroxyzine hydrochloride. The generic version typically costs $4-$8 per month without insurance. With prescription coverage, it may be available for less than $5 per month.
Vistaril and Atarax are older antihistamine medications that have become economical generic drugs. Their low cost makes them accessible and budget-friendly choices compared to newer brand name anti-anxiety medications.
Patients looking to reduce anxiety symptoms often find the generic versions of Vistaril and Atarax to be cost-effective options, both with and without prescription drug coverage. Discussing medication costs with your healthcare provider can help determine if one of these affordable generics may be a good fit for you.
The Bottom Line
Vistaril and Atarax are essentially the same medication— both medications are antihistamines that also have anti-anxiety and sedative properties. They work by blocking histamine receptors in the body that can cause allergy symptoms as well as anxiety.
For treating anxiety, studies show that Atarax and Vistaril can be as effective as benzodiazepines like Valium or Xanax but with less risk of dependence and abuse. The effects come on more slowly but last longer.
Overall, Vistaril and Atarax are very similar medications that are moderately effective for anxiety treatment. Vistaril is often preferred because it is the generic version and therefore more widely available and affordable. However, Atarax may be covered by more insurance plans since it is the brand name.
Talk to your doctor about whether Atarax or Vistaril is better for your specific anxiety symptoms and treatment plan. The most important factor is that you have access to an affordable medication that provides anxiety relief with minimal side effects.
Learn the differences between Vistaril and Atarax, two antihistamines used for anxiety. This guide explains their similarities, side effects, dosage, and more.
Share this post:
Sign up for blog updates!
Join my email list to receive updates and information.